Abstract B030: Combined inhibition of BET proteins and PARP

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dna bet These elongation factors work closely with RNA polymerase II to keep transcription running smoothly BET proteins can interact with these  Using BRDT as a model, we characterized how the BET family of bromodomains interacts with site-specifically acetylated nucleosomes Here we  The present results confirm that BET proteins directly regulate the HR-directed DNA repair and that the inhibition of this family of chromatin readers induces

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